【Vilber Installation】Vilber multifunctional in vivo optical imaging system settled in college of pharmaceutical science, Zhejiang University of Technology

Recently, Vilber Fusion FX 7 multi-functional in vivo imaging arrived in Hangzhou and settled in the team of Professor Yang Gensheng of School of Pharmacy, Zhejiang University of Technology. The successful installation and commissioning will assist Professor Yang Gensheng's team in the design and preparation of biological materials and the delivery and release of vaccines and drugs.

The FUSION FX 7 multi-functional small animal live / plant imaging system has the functions of fluorescence, bioluminescence, and chemiluminescence. The system combines the characteristics of high sensitivity, high light signal acquisition capability, and user-friendly operation interface.

The system uses a new generation of deep-cooled CCD camera, dark current 0.0001e/p/s@-90℃, cooling speed is faster and longer life; f0.7 super lens, greatly increase the amount of light entering per unit time, which is effective Shorten the exposure time, especially suitable for bioluminescence imaging of Luc reporter gene detection; fluorescent imaging uses pulsed LED light source, 7 channels, and the excitation intensity is higher than that of halogen lamp. Based on the scanning method, the excitation uniformity is ≥99%; fully automatic control of the 7-bit emission filter wheel, equipped with 6 special narrow-wave filters, covering 400 ~ 900nm, to meet the detection needs of a variety of dyes; equipped with special temperature control for mice The table is compatible with the mouse anesthesia system, with a maximum throughput of up to 5 mice.
The system can be applied to fluorescence and bioluminescence imaging in mice, tracking cell migration in vivo or in vitro, can superimpose signals, and can simultaneously display multiple reporter genes; applied to tumor development, stem cells, immune related diseases, metabolic diseases, drug metabolism And research on the molecular mechanism of diseases. The system can also be used for the research of plant gene expression regulation, transgene identification, plant stress, mutant screening, microbial infection, plant biological rhythm and other fields. Can meet GFP, YFP, Pro-Q Emerald 300, Sypro-Ruby, FITC, DAPI, Alexa Fluor680, 700, 750, Cy3, Cy5, Cy5.5, Cy7, mCherry and other fluorescent dyes。